NEW YORK—Researchers at the Mount Sinai School of Medicine were hardly able to stifle their laughter Tuesday while administering a placebo to 25 patients participating in a single-blind trial of an experimental new emphysema drug. "Did you see Participant No. 425? He was like, 'I think it's really working, Doc,'" Dr. Lewis Rodriguez said to a team of snickering pulmonary specialists. "How gullible can you get? I can't believe those guys think they're actually getting CDDO-Im." Although the trial is expected to run for two more months, Rodriguez told reporters that he almost could not wait to analyze the data, compile the results, publish the findings, and see the looks on their stupid faces.